We can encapsulate cancer cell lines, primary cell lines, iPSC, iPS-derived cells (differentiated), and patient-derived cells.

We have a broad range of chips to control the size of the capsule.

The size of the capsule varies between 200 - 600 µm.

The capsules are compatible with molecules of which molecular weight is below 100 kDa. However, we invented a new technology allowing big particles, up to the size of viruses, to cross the capsule.

The size of the spheroid/organoids depends on the cell line, the size of the capsule, the initial number of encapsulated cells, and the age of the spheroid/organoid, however, the size is between 100-500 µm.

The minimal number of cells depends on the type of cells. For cancer cell lines, we use approximately 50 cells.

Since the size of the spheroid/organoid can be controlled under 300 µm, we drastically limit necrosis in our encapsulated tissues.

After one week of encapsulation, there are on average 200 cells per spheroid/organoid.

The maximal number of tissues we can mix and measure is 5. Today, we can use in routine 3 tissues simultaneously.

We use alginate that is a neutral molecule (algae sugar) well described in the literature to poorly interact with most molecules. The cells grow very fast within the capsules, showing that all the nutrients and molecules that they need can easily diffuse through the capsule.