Holistic view of drug systemic response with human systemic phenotypic assays comprising healthy tissues, disease models, and drug-metabolizing tissues, coupled with omics analyses.

Flexible combinations of multi-tissue systems to interfere with systemic organ communications and to dissect their precise interplay in the drug systemic response.

Deep characterization of the mechanism of action and identification of biomarkers with a human and systemic relevance to be actionable by clinicians for better drug development.